Interactor 1: WRN (Q14191)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 5.6.2.4) (DNA 3'-5' helicase WRN)]
Gene: WRN
Interactor 2: PAXX (Q9BUH6)
Protein PAXX (Paralog of XRCC4 and XLF) (XRCC4-like small protein)
Gene: PAXX
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.55 | 0.513 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006974 - DNA damage response GO:0042803 - protein homodimerization activity |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
