HitPredict

Interactor 1: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Interactor 2: TNIK (Q9UKE5)
TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1278 Hs			1 1360
+	Rn
		222472 MRCKA_RAT (154-593): 3.97e-21: 102: 15.78		MRCKA_RAT (12-1330): 0: 699: 14.04
+	Hs
		1137871 MRCKA_HUMAN (154-593): 9.15e-20: 98.4: 15.64		MRCKA_HUMAN (12-1330): 0: 690: 13.75
+	Rn
		222476 MRCKA_RAT (154-593): 3.97e-21: 102: 15.78		MRCKB_RAT (15-1330): 0: 661: 14.77
+	Hs
		1137917 MRCKA_HUMAN (154-593): 9.15e-20: 98.4: 15.64		MRCKB_HUMAN (15-1330): 0: 661: 15.04
+	Hs
		1051494 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		STK26_HUMAN (16-400): 7.78e-113: 362: 38.27
+	Hs
		522545 MYH1_HUMAN (374-1278): 2.47e-39: 162: 10.82		STK4_HUMAN (5-482): 7.72e-121: 387: 33.06
+	Hs
		675140 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		KS6A3_HUMAN (10-709): 1.25e-135: 435: 16.74
+	Hs
		522546 MYH1_HUMAN (374-1278): 2.47e-39: 162: 10.82		STK3_HUMAN (4-485): 1.79e-115: 372: 29.28
+	Hs
		682199 CLIP3_HUMAN (10-139): 7.2e-31: 131: 31.34		AKT2_HUMAN (3-352): 5.78e-123: 392: 22.87
+	Hs
		725242 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		SIK2_HUMAN (15-915): 3.97e-124: 410: 14.70
+	Ce
		104563 G5EBY3_CAEEL (95-573): 1.87e-15: 84.2: 16.84		PAR1_CAEEL (1-909): 5.01e-129: 430: 14.66
+	Hs
		725223 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		MARK4_HUMAN (7-748): 2.35e-123: 403: 18.00
+	Hs
		522609 MYH7_HUMAN (64-763): 2.65e-27: 122: 9.80		STK4_HUMAN (5-482): 7.72e-121: 387: 33.06
+	Hs
		528369 MYH6_HUMAN (47-712): 5.82e-26: 118: 9.71		STK4_HUMAN (5-482): 7.72e-121: 387: 33.06
+	Hs
		522610 MYH7_HUMAN (64-763): 2.65e-27: 122: 9.80		STK3_HUMAN (4-485): 1.79e-115: 372: 29.28
+	Hs
		725010 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		SIK2_HUMAN (15-915): 3.97e-124: 410: 14.70
+	Hs
		1023138 MYH13_HUMAN (637-1278): 2.11e-21: 103: 10.87		STK4_HUMAN (5-482): 7.72e-121: 387: 33.06
+	Hs
		528371 MYH6_HUMAN (47-712): 5.82e-26: 118: 9.71		STK3_HUMAN (4-485): 1.79e-115: 372: 29.28
+	Hs
		724967 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		MARK4_HUMAN (7-748): 2.35e-123: 403: 18.00
+	Hs
		1027453 MYH13_HUMAN (637-1278): 2.11e-21: 103: 10.87		STK3_HUMAN (4-485): 1.79e-115: 372: 29.28