HitPredict

Interactor 1: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Interactor 2: NINL (Q9Y2I6)
Ninein-like protein
Gene: NINL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27173435, 28718761, 26485645
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0005874 - microtubule GO:0034454 - microtubule anchoring at centrosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1278 Hs			1 1382
+	Hs
		675251 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		NINL_HUMAN (1-1382): 4.31e-101: 355: 100.00
+	Hs
		1051363 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		NIN_HUMAN (744-1382): 1.66e-14: 81.5: 12.90
+	Hs
		725033 KI13B_HUMAN (14-145): 4.98e-32: 138: 32.85		MYH9_HUMAN (741-1382): 4.98e-21: 102: 11.79
+	Hs
		522657 MYH7_HUMAN (64-763): 2.65e-27: 122: 9.80		MYH4_HUMAN (762-1382): 9.46e-20: 98.5: 8.17
+	Hs
		725095 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		MYH10_HUMAN (802-1375): 9.91e-23: 108: 10.59
+	Hs
		725097 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		MYH11_HUMAN (806-1382): 1.58e-22: 107: 10.17
+	Hs
		675226 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		CP250_HUMAN (3-995): 1.16e-23: 111: 10.67
+	Hs
		724687 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		MYH9_HUMAN (741-1382): 4.98e-21: 102: 11.79
+	Hs
		528356 MYH6_HUMAN (47-712): 5.82e-26: 118: 9.71		MYH6_HUMAN (804-1382): 8.3e-18: 92.3: 10.75
+	Hs
		502901 MYH6_HUMAN (47-712): 5.82e-26: 118: 9.71		MYH3_HUMAN (842-1379): 3.1e-17: 90.4: 8.55
+	Hs
		502921 CLIP4_HUMAN (6-95): 3.79e-26: 118: 42.22		MYH3_HUMAN (842-1379): 3.1e-17: 90.4: 8.55
+	Hs
		522585 MYH7_HUMAN (64-763): 2.65e-27: 122: 9.80		MYH7_HUMAN (986-1363): 1.07e-10: 68.9: 13.02
+	Hs
		502933 MYH4_HUMAN (726-1276): 1.05e-18: 94.9: 10.20		MYH3_HUMAN (842-1379): 3.1e-17: 90.4: 8.55
+	Hs
		528432 MYH13_HUMAN (637-1278): 2.11e-21: 103: 10.87		MYH8_HUMAN (3-589): 1.15e-14: 81.9: 11.99
+	Hs
		1233482 MYH13_HUMAN (637-1278): 2.11e-21: 103: 10.87		NIN_HUMAN (744-1382): 1.66e-14: 81.5: 12.90
+	Hs
		675202 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		NIN_HUMAN (744-1382): 1.66e-14: 81.5: 12.90
+	Hs
		724686 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		MYH9_HUMAN (741-1382): 4.98e-21: 102: 11.79
+	Hs
		528435 MYH4_HUMAN (726-1276): 1.05e-18: 94.9: 10.20		MYH8_HUMAN (3-589): 1.15e-14: 81.9: 11.99
+	Rn
		222476 MRCKA_RAT (154-593): 3.97e-21: 102: 15.78		MRCKB_RAT (385-817): 9.45e-11: 69.1: 19.37