HitPredict

Interactor 1: DYHC1 (Q14204)
Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)
Gene: DYNC1H1

Interactor 2: DAPLE (Q9P219)
Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) (hDaple) (Hook-related protein 2) (HkRP2)
Gene: CCDC88C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28718761
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0031122 - cytoplasmic microtubule organization GO:0051959 - dynein light intermediate chain binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 4646 Hs			1 2028
+	Hs
		1051558 DYHC1_HUMAN (1-4646): 0: 4190: 100.00		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		1051540 DYHC1_HUMAN (1-4646): 0: 4190: 100.00		NUMA1_HUMAN (2-1111): 1.36e-36: 154: 11.67
+	Hs
		1051598 DYHC1_HUMAN (1-4646): 0: 4190: 100.00		HOOK3_HUMAN (4-548): 2.59e-25: 116: 24.56
+	Hs
		148802 DYHC1_HUMAN (1-4646): 0: 4190: 100.00		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		1051707 DYHC1_HUMAN (1-4646): 0: 4190: 100.00		HOOK1_HUMAN (17-682): 7.93e-18: 92: 23.98
+	Hs
		1051553 DYHC1_HUMAN (1-4646): 0: 4190: 100.00		ITSN1_HUMAN (60-424): 6.95e-14: 79.9: 11.52
+	Hs
		1061237 DYH6_HUMAN (931-4645): 0: 3457: 25.66		NUMA1_HUMAN (2-1111): 1.36e-36: 154: 11.67
+	Hs
		148969 DYH12_HUMAN (3846-4645): 0: 867: 21.83		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		1061276 DYH2_HUMAN (9-1477): 4.2e-18: 95.6: 9.79		NUMA1_HUMAN (2-1111): 1.36e-36: 154: 11.67
+	Hs
		149065 DYHC2_HUMAN (78-753): 2.51e-11: 72.9: 9.53		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39