HitPredict

Interactor 1: IF4A2 (Q14240)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: EIF4A2

Interactor 2: EIF3C (Q99613)
Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) (eIF3 p110)
Gene: EIF3C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29395067, 24981860
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003743 - translation initiation factor activity GO:0005829 - cytosol GO:0006413 - translational initiation
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 913
+	Hs
		892881 IF4A1_HUMAN (3-407): 2.35e-159: 456: 89.88		EIF3C_HUMAN (1-913): 0: 1213: 100.00
+	Hs
		134181 DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51		EIF3C_HUMAN (1-913): 0: 1213: 100.00
+	Sc
		485678 IF4A_YEAST (24-407): 7e-167: 474: 65.89		EIF3C_YEAST (5-256): 8.62e-18: 90.6: 21.53