HitPredict

Interactor 1: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Interactor 2: SF3B4 (Q15427)
Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (Spliceosome-associated protein 49) (SAP 49)
Gene: SF3B4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.50	0.535

Property	Details
Experiments	24981860, 34133714
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 424
+	Hs
		1073578 ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99		SF3B4_HUMAN (1-424): 5.15e-61: 205: 100.00
+	Mm
		857330 PACN1_MOUSE (241-549): 1.99e-32: 131: 17.46		TIA1_MOUSE (6-86): 4.82e-10: 63: 27.16
+	Ce
		70034 SH3GH_CAEEL (358-548): 3.11e-12: 70.2: 22.00		Q17350_CAEEL (11-183): 5.03e-10: 63.5: 23.96
+	Ce
		70032 SH3GH_CAEEL (358-548): 3.11e-12: 70.2: 22.00		SF3B4_CAEEL (88-364): 3.32e-10: 63.3: 14.79
+	Dm
		53017 A1Z866_DROME (490-548): 7.88e-12: 70: 34.43		Q9W424_DROME (96-385): 5.7e-09: 59.5: 16.72