HitPredict

Interactor 1: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Interactor 2: NDE1 (Q9NXR1)
Nuclear distribution protein nudE homolog 1 (NudE)
Gene: NDE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 335
+	Hs
		724825 SRC8_HUMAN (1-550): 0: 559: 100.00		MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18
+	Hs
		724801 MYO1E_HUMAN (165-549): 3.1e-44: 170: 15.01		MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18
+	Hs
		522612 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		MYH7_HUMAN (3-226): 2.27e-35: 138: 12.95
+	Hs
		207844 PPIP1_HUMAN (198-549): 4.97e-33: 132: 15.18		MYH13_HUMAN (3-243): 1.12e-35: 139: 12.03
+	Hs
		724817 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18
+	Hs
		787985 ITSN2_HUMAN (398-548): 1.14e-18: 92.3: 17.88		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		61732 A6H8W8_HUMAN (398-548): 1.72e-18: 91.9: 17.88		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Cl
		47357 F1PHV6_CANLF (274-548): 7.81e-14: 77: 11.46		A0A8I3PJA6_CANLF (4-255): 9.4e-43: 159: 14.82
+	Hs
		787920 ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Rn
		92844 ITSN1_RAT (186-549): 1.31e-15: 82.8: 12.50		E9PSY8_RAT (4-255): 1.13e-35: 139: 13.76
+	Mm
		788010 ITSN1_MOUSE (49-549): 1.84e-16: 85.5: 13.61		EPS15_MOUSE (4-255): 4.39e-34: 134: 11.90
+	Hs
		298957 SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91		MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18
+	Hs
		1078856 ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99		MYH14_HUMAN (2-211): 4.08e-18: 87.7: 17.62