HitPredict

Interactor 1: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Interactor 2: RAI14 (Q9P0K7)
Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14)
Gene: RAI14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~SH3_9
Common GO terms	GO:0005829 - cytosol GO:0005938 - cell cortex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 550 Hs			1 980
+	Hs
		1052276 SRC8_HUMAN (1-550): 0: 559: 100.00		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		862039 SRC8_HUMAN (1-550): 0: 559: 100.00		DAPK1_HUMAN (111-426): 2.39e-29: 128: 12.03
+	Hs
		1021686 MYO1E_HUMAN (165-549): 3.1e-44: 170: 15.01		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		1349607 PACN2_HUMAN (176-550): 4.93e-40: 153: 15.37		RAI14_HUMAN (1-980): 4.28e-77: 274: 100.00
+	Hs
		1045471 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		1315999 PACN1_HUMAN (241-549): 2.37e-31: 128: 16.86		RAI14_HUMAN (1-980): 4.28e-77: 274: 100.00
+	Hs
		1021703 MYO1E_HUMAN (165-549): 3.1e-44: 170: 15.01		Q9H4D1_HUMAN (11-256): 9.8e-49: 188: 24.29
+	Hs
		1078921 ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99		RAI14_HUMAN (1-980): 4.28e-77: 274: 100.00
+	Hs
		883497 MYO1E_HUMAN (165-549): 3.1e-44: 170: 15.01		RIPK4_HUMAN (4-181): 1.95e-43: 172: 30.73
+	Hs
		1021399 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		ANK3_HUMAN (24-405): 2.11e-47: 187: 18.74
+	Hs
		257713 ITSN2_HUMAN (398-548): 1.14e-18: 92.3: 17.88		ANR17_HUMAN (3-464): 1.19e-59: 226: 18.30
+	Mm
		82740 B9EKJ1_MOUSE (213-549): 9.53e-34: 139: 14.12		ANK3_MOUSE (60-438): 3.15e-42: 170: 21.37
+	Hs
		1078859 ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99		MIB1_HUMAN (1-552): 5.8e-59: 221: 18.56
+	Hs
		1206011 STAM1_HUMAN (416-546): 2.82e-13: 74.4: 21.83		MIB1_HUMAN (1-552): 5.8e-59: 221: 18.56
+	Hs
		862037 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		DAPK1_HUMAN (111-426): 2.39e-29: 128: 12.03
+	Hs
		1257082 PACN1_HUMAN (241-549): 2.37e-31: 128: 16.86		ANR24_HUMAN (649-980): 2.45e-26: 119: 30.03
+	Hs
		883589 STAM1_HUMAN (416-546): 2.82e-13: 74.4: 21.83		RIPK4_HUMAN (4-181): 1.95e-43: 172: 30.73
+	Hs
		1021717 MYO1E_HUMAN (165-549): 3.1e-44: 170: 15.01		ANR50_HUMAN (133-352): 3.59e-13: 76.2: 16.82
+	Hs
		167009 SH3G3_HUMAN (365-549): 5.45e-31: 125: 18.82		ANR28_HUMAN (156-405): 1.15e-12: 74.2: 14.00
+	Rn
		193489 O35823_RAT (332-547): 4.77e-29: 123: 20.32		CSKI1_RAT (177-289): 2.77e-10: 66.9: 17.70