Interactor 1: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Interactor 2: SHAN2 (Q9UPX8)
SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin-binding protein 1) (CortBP1) (Proline-rich synapse-associated protein 1)
Gene: SHANK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.713

The method score is based on:

Property Details
Experiments 9742101
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~SH3_9, SH3_2~SH3_9
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0043197 - dendritic spine
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 550
Hs

1 1849
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024