HitPredict

Interactor 1: FLOT2 (Q14254)
Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1)
Gene: FLOT2

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 428 Hs			1 232
+	Hs
		901158 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RND3_HUMAN (1-232): 1.75e-100: 293: 58.20
+	Hs
		894002 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		852471 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		925277 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		892369 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		914069 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		545373 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		900464 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		950993 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		436299 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		915676 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120435 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		1052489 FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21
+	Hs
		279496 FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		279487 FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		279495 FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		279425 FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		279500 FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		279407 FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		120248 FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76