HitPredict

Interactor 1: TRI25 (Q14258)
E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147)
Gene: TRIM25

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29117863, 28515276
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 630 Hs			1 972
+	Hs
		531152 TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00		EF2_HUMAN (111-957): 0: 915: 38.16
+	Hs
		1064608 TRI47_HUMAN (11-630): 3.83e-81: 270: 23.71		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1049029 TRI14_HUMAN (155-624): 1.74e-75: 249: 18.45		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1064423 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		531188 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		EF2_HUMAN (111-957): 0: 915: 38.16
+	Mm
		885401 TRI27_MOUSE (2-358): 4.29e-31: 129: 14.95		EF2_MOUSE (111-957): 0: 916: 38.16
+	Hs
		1171331 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		EFGM_HUMAN (107-932): 0: 585: 19.64
+	Hs
		1170574 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		EFL1_HUMAN (115-488): 1.56e-126: 412: 28.13