HitPredict

Interactor 1: TRI25 (Q14258)
E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147)
Gene: TRIM25

Interactor 2: ZFHX3 (Q15911)
Zinc finger homeobox protein 3 (AT motif-binding factor 1) (AT-binding transcription factor 1) (Alpha-fetoprotein enhancer-binding protein) (Zinc finger homeodomain protein 3) (ZFH-3)
Gene: ZFHX3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22452784
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016604 - nuclear body
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 630 Hs			1 3703
+	Hs
		1080550 TRIMM_HUMAN (156-626): 9.21e-77: 253: 19.00		ZFHX3_HUMAN (1-3703): 0: 1661: 100.00
+	Hs
		536845 TRI27_HUMAN (2-358): 2.11e-31: 130: 14.40		ZFHX3_HUMAN (1-3703): 0: 1661: 100.00
+	Hs
		1128449 TRI39_HUMAN (4-351): 6.55e-31: 128: 17.40		ZN484_HUMAN (516-1135): 1.36e-117: 398: 12.01
+	Hs
		1137069 TRI39_HUMAN (4-351): 6.55e-31: 128: 17.40		ZN658_HUMAN (2007-2878): 8.47e-74: 272: 6.50
+	Hs
		1261120 TRI41_HUMAN (197-628): 1.4e-79: 266: 16.70		RBAK_HUMAN (1090-1617): 1.97e-19: 98.5: 18.61
+	Hs
		536852 TRI27_HUMAN (2-358): 2.11e-31: 130: 14.40		ZN423_HUMAN (1187-2010): 8.11e-30: 133: 10.61
+	Hs
		1350390 TRI10_HUMAN (2-331): 7.51e-29: 122: 16.81		ZN624_HUMAN (2567-2794): 1.22e-10: 70.1: 7.90