HitPredict

Interactor 1: TRI25 (Q14258)
E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147)
Gene: TRIM25

Interactor 2: UBP39 (Q53GS9)
Ubiquitin carboxyl-terminal hydrolase 39 (EC 3.4.19.12) (SAD1 homolog) (U4/U6.U5 tri-snRNP-associated 65 kDa protein)
Gene: USP39

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	23105109
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 630 Hs			1 565
+	Hs
		1121194 TRIM8_HUMAN (7-358): 1.75e-77: 258: 25.21		UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00
+	Hs
		800581 TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00		UBP5_HUMAN (13-493): 7.35e-87: 288: 15.81
+	Hs
		1121162 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00
+	Hs
		271214 TRIM1_HUMAN (3-629): 8.74e-115: 361: 20.58		UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83
+	Hs
		1273855 TRIM8_HUMAN (7-358): 1.75e-77: 258: 25.21		UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06
+	Hs
		1171100 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06
+	Hs
		271188 TRIM9_HUMAN (4-591): 2.11e-79: 267: 14.85		UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83
+	Hs
		271187 TRIM8_HUMAN (7-358): 1.75e-77: 258: 25.21		UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83
+	Hs
		1172289 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		UBP22_HUMAN (123-560): 1.99e-114: 351: 17.39
+	Hs
		271128 TRI46_HUMAN (4-622): 3.72e-69: 241: 15.24		UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83
+	Hs
		1318685 TRIM9_HUMAN (4-591): 2.11e-79: 267: 14.85		UBP21_HUMAN (223-560): 2.89e-97: 308: 18.85
+	Hs
		777049 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		UBP8_HUMAN (177-564): 2.41e-101: 332: 19.80
+	Hs
		1318357 TRIM8_HUMAN (7-358): 1.75e-77: 258: 25.21		UBP21_HUMAN (223-560): 2.89e-97: 308: 18.85
+	Hs
		800626 TRIM8_HUMAN (7-358): 1.75e-77: 258: 25.21		UBP5_HUMAN (13-493): 7.35e-87: 288: 15.81
+	Hs
		800594 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		UBP5_HUMAN (13-493): 7.35e-87: 288: 15.81
+	Hs
		1024331 TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00		UBP4_HUMAN (222-340): 1.69e-10: 65.9: 33.33
+	Hs
		271189 TRIM5_HUMAN (2-281): 6.42e-32: 131: 15.19		UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83
+	Hs
		800627 TRIM5_HUMAN (2-281): 6.42e-32: 131: 15.19		UBP5_HUMAN (13-493): 7.35e-87: 288: 15.81
+	Hs
		1024364 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		UBP4_HUMAN (222-340): 1.69e-10: 65.9: 33.33
+	Hs
		850096 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		UBP11_HUMAN (439-556): 3.89e-09: 61.6: 31.09