HitPredict

Interactor 1: TRI25 (Q14258)
E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147)
Gene: TRIM25

Interactor 2: RN135 (Q8IUD6)
E3 ubiquitin-protein ligase RNF135 (EC 2.3.2.27) (RIG-I E3 ubiquitin ligase) (REUL) (RING finger protein 135) (RING finger protein leading to RIG-I activation) (Riplet) (RING-type E3 ubiquitin transferase RNF135)
Gene: RNF135

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35913217
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PRY~SPRY, SPRY~SPRY
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010494 - cytoplasmic stress granule
GO:0039552 - RIG-I binding
and 4 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024