HitPredict

Interactor 1: TRI25 (Q14258)
E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147)
Gene: TRIM25

Interactor 2: OTUB2 (Q96DC9)
Ubiquitin thioesterase OTUB2 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB2) (OTU domain-containing ubiquitin aldehyde-binding protein 2) (Otubain-2) (Ubiquitin-specific-processing protease OTUB2)
Gene: OTUB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	23105109
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 630 Hs			1 234
+	Hs
		175705 TRI18_HUMAN (4-629): 4.7e-124: 383: 22.17		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		1288105 TRIM1_HUMAN (3-629): 8.74e-115: 361: 20.58		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		1288092 TRIM8_HUMAN (7-358): 1.75e-77: 258: 25.21		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		1171210 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		OTUB1_HUMAN (8-230): 3.11e-110: 319: 47.56
+	Hs
		1288093 TRIM5_HUMAN (2-281): 6.42e-32: 131: 15.19		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		536975 TRI27_HUMAN (2-358): 2.11e-31: 130: 14.40		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		1288099 TRI39_HUMAN (4-351): 6.55e-31: 128: 17.40		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00
+	Hs
		585031 RO52_HUMAN (72-325): 5.42e-14: 76.6: 13.36		OTUB2_HUMAN (1-234): 1.5e-114: 328: 100.00