HitPredict

Interactor 1: TRI25 (Q14258)
E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147)
Gene: TRIM25

Interactor 2: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29117863, 33436560
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 630 Hs			1 577
+	Hs
		128175 TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		128174 TRI14_HUMAN (155-624): 1.74e-75: 249: 18.45		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		128217 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1052819 TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		128021 RO52_HUMAN (72-325): 5.42e-14: 76.6: 13.36		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1052662 TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		1049037 TRI14_HUMAN (155-624): 1.74e-75: 249: 18.45		PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43
+	Hs
		1072117 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43
+	Hs
		884386 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		PCBP4_HUMAN (268-572): 4.28e-31: 127: 17.91
+	Hs
		1172490 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1171244 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		1049105 TRI14_HUMAN (155-624): 1.74e-75: 249: 18.45		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		1171135 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		1171090 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		1071912 TRI67_HUMAN (48-591): 3.42e-69: 241: 15.73		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		884393 TRI11_HUMAN (6-288): 2.34e-31: 129: 19.08		PCBP4_HUMAN (268-572): 4.28e-31: 127: 17.91