HitPredict

Interactor 1: SYNJ (G5ECL2)
Synaptojanin (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase) (Uncoordinated protein 26)
Gene: unc-26

Interactor 2: Q95PW9 (Q95PW9)
NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family
Gene: nck-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1119 Ce			1 395
+	Hs
		166030 SYNJ2_HUMAN (3-1106): 0: 1040: 32.66		NCK1_HUMAN (2-394): 6.74e-80: 252: 37.78
+	Ce
		105275 SYNJ_CAEEL (1-1097): 0: 1122: 100.00		SRC1_CAEEL (214-378): 5.96e-19: 90.5: 32.20
+	Ce
		105281 SYNJ_CAEEL (1-1097): 0: 1122: 100.00		Q9U2T9_CAEEL (2-58): 6.33e-11: 66.2: 26.67
+	Hs
		166056 SYNJ2_HUMAN (3-1106): 0: 1040: 32.66		ITSN2_HUMAN (8-285): 3.74e-34: 136: 19.61
+	Hs
		166049 SYNJ2_HUMAN (3-1106): 0: 1040: 32.66		ITSN1_HUMAN (5-269): 1.04e-31: 129: 14.46
+	Hs
		166042 SYNJ2_HUMAN (3-1106): 0: 1040: 32.66		GRB2_HUMAN (5-175): 1.72e-28: 112: 20.37
+	Hs
		166032 SYNJ2_HUMAN (3-1106): 0: 1040: 32.66		P85A_HUMAN (270-393): 4.44e-20: 94.5: 19.69
+	Hs
		166024 SYNJ2_HUMAN (3-1106): 0: 1040: 32.66		FYN_HUMAN (6-244): 7.07e-19: 90.2: 12.45
+	Dm
		993185 Q5U0V7_DROME (3-1115): 0: 1044: 37.84		GRAP_DROME (2-59): 1.56e-15: 76.7: 27.59
+	Dm
		112574 Q5U0V7_DROME (3-1115): 0: 1044: 37.84		M9ND00_DROME (4-76): 6.13e-14: 75.9: 24.66
+	Mm
		1159873 SHIP2_MOUSE (487-1111): 5.02e-127: 421: 19.57		ITSN1_MOUSE (1-283): 1.65e-58: 207: 23.00
+	Hs
		411678 OCRL_HUMAN (482-919): 8.02e-120: 393: 29.67		LCK_HUMAN (176-378): 5.2e-55: 190: 30.05
+	Hs
		176448 SHIP2_HUMAN (487-1103): 3.02e-130: 429: 19.55		ITSN1_HUMAN (5-269): 1.04e-31: 129: 14.46
+	Mm
		1141165 SHIP1_MOUSE (486-1116): 2.08e-132: 434: 17.63		GRB2_MOUSE (5-175): 1.35e-28: 113: 20.83
+	Hs
		176424 SHIP2_HUMAN (487-1103): 3.02e-130: 429: 19.55		GRB2_HUMAN (5-175): 1.72e-28: 112: 20.37
+	Mm
		643112 SHIP1_MOUSE (486-1116): 2.08e-132: 434: 17.63		P85A_MOUSE (270-393): 5.53e-20: 94.1: 19.69
+	Hs
		176388 SHIP2_HUMAN (487-1103): 3.02e-130: 429: 19.55		P85A_HUMAN (270-393): 4.44e-20: 94.5: 19.69
+	Hs
		129144 SHIP2_HUMAN (487-1103): 3.02e-130: 429: 19.55		P85B_HUMAN (281-394): 1.24e-18: 89.8: 22.22
+	Mm
		403460 SHIP1_MOUSE (486-1116): 2.08e-132: 434: 17.63		SRC_MOUSE (43-180): 9.38e-12: 68.3: 21.58
+	Mm
		729763 SHIP1_MOUSE (486-1116): 2.08e-132: 434: 17.63		BTK_MOUSE (2-129): 7.13e-11: 66: 17.05