HitPredict

Interactor 1: SYNJ (G5ECL2)
Synaptojanin (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase) (Uncoordinated protein 26)
Gene: unc-26

Interactor 2: Q9U2T9 (Q9U2T9)
Intersectin-1
Gene: itsn-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1119 Ce			1 1085
+	Ce
		105280 SYNJ_CAEEL (1-1097): 0: 1122: 100.00		Q95PW9_CAEEL (670-843): 3.79e-09: 62: 26.55
+	Hs
		166030 SYNJ2_HUMAN (3-1106): 0: 1040: 32.66		NCK1_HUMAN (887-1082): 7.16e-35: 139: 22.27
+	Hs
		166056 SYNJ2_HUMAN (3-1106): 0: 1040: 32.66		ITSN2_HUMAN (475-1085): 1.13e-26: 120: 14.82
+	Hs
		166049 SYNJ2_HUMAN (3-1106): 0: 1040: 32.66		ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35
+	Dm
		112574 Q5U0V7_DROME (3-1115): 0: 1044: 37.84		M9ND00_DROME (622-1084): 9.53e-14: 78.3: 13.79
+	Hs
		166042 SYNJ2_HUMAN (3-1106): 0: 1040: 32.66		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		166060 SYNJ2_HUMAN (3-1106): 0: 1040: 32.66		CD2AP_HUMAN (600-725): 2.26e-11: 70.1: 22.22
+	Hs
		176448 SHIP2_HUMAN (487-1103): 3.02e-130: 429: 19.55		ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35
+	Hs
		557759 SHIP1_HUMAN (485-1117): 9.64e-109: 369: 18.46		NCK1_HUMAN (887-1082): 7.16e-35: 139: 22.27
+	Mm
		1141165 SHIP1_MOUSE (486-1116): 2.08e-132: 434: 17.63		GRB2_MOUSE (1030-1085): 5.12e-13: 71.3: 33.33
+	Mm
		1159873 SHIP2_MOUSE (487-1111): 5.02e-127: 421: 19.57		ITSN1_MOUSE (780-940): 1.48e-14: 81: 26.95
+	Hs
		176424 SHIP2_HUMAN (487-1103): 3.02e-130: 429: 19.55		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		176509 SHIP2_HUMAN (487-1103): 3.02e-130: 429: 19.55		CD2AP_HUMAN (600-725): 2.26e-11: 70.1: 22.22
+	Hs
		924485 OCRL_HUMAN (482-919): 8.02e-120: 393: 29.67		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		298971 OCRL_HUMAN (482-919): 8.02e-120: 393: 29.67		SRBS2_HUMAN (890-1084): 1.68e-09: 64.3: 27.20
+	Hs
		924742 SHIP1_HUMAN (485-1117): 9.64e-109: 369: 18.46		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		1271571 SHIP1_HUMAN (485-1117): 9.64e-109: 369: 18.46		CD2AP_HUMAN (600-725): 2.26e-11: 70.1: 22.22
+	Rn
		1126747 SYNJ1_RAT (797-1110): 6.05e-10: 65.9: 7.89		Q5JC29_RAT (4-469): 4.23e-57: 214: 20.34
+	Rn
		192744 SYNJ1_RAT (797-1110): 6.05e-10: 65.9: 7.89		SRBS2_RAT (589-1020): 1.89e-35: 148: 13.73
+	Hs
		203192 SYNJ1_HUMAN (892-1118): 5.28e-09: 62.8: 10.44		SRBS2_HUMAN (890-1084): 1.68e-09: 64.3: 27.20