HitPredict

Interactor 1: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	21182203
Identification Methods	affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2725 Hs			1 530
+	Hs
		598256 FLNA_HUMAN (167-2725): 0: 1226: 35.27		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		261304 FLNB_HUMAN (146-2725): 0: 1198: 35.18		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368984 FLNA_HUMAN (167-2725): 0: 1226: 35.27		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		261174 FLNB_HUMAN (146-2725): 0: 1198: 35.18		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		487127 FLNA_HUMAN (167-2725): 0: 1226: 35.27		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		521591 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		211633 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		993279 ACTN3_HUMAN (23-388): 4.53e-120: 406: 27.63		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368893 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		211456 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369420 SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370043 SYNE1_HUMAN (33-344): 6.35e-100: 364: 28.65		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		521532 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		NR1H3_HUMAN (65-499): 1.77e-104: 322: 20.97
+	Hs
		957553 PGBM_HUMAN (1306-2725): 4.84e-73: 276: 11.87		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		211472 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Hs
		362739 FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Mm
		580490 ACTN2_MOUSE (2-387): 2.32e-122: 412: 26.00		ANDR_MOUSE (149-407): 1.53e-38: 152: 33.70
+	Hs
		211471 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		377720 MXRA5_HUMAN (1436-2543): 4.42e-17: 91.3: 11.61		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		362738 FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59