HitPredict

Interactor 1: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Interactor 2: CHM4C (Q96CF2)
Charged multivesicular body protein 4c (Chromatin-modifying protein 4c) (CHMP4c) (SNF7 homolog associated with Alix 3) (SNF7-3) (hSnf7-3) (Vacuolar protein sorting-associated protein 32-3) (Vps32-3) (hVps32-3)
Gene: CHMP4C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2725 Hs			1 233
+	Hs
		1052937 FLNC_HUMAN (1-2725): 0: 2507: 100.00		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		598265 FLNA_HUMAN (167-2725): 0: 1226: 35.27		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		261308 FLNB_HUMAN (146-2725): 0: 1198: 35.18		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		598318 FLNA_HUMAN (167-2725): 0: 1226: 35.27		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		261326 FLNB_HUMAN (146-2725): 0: 1198: 35.18		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		521595 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		725686 ACTN2_HUMAN (2-387): 2.32e-122: 412: 26.00		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		211642 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		993280 ACTN3_HUMAN (23-388): 4.53e-120: 406: 27.63		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		521612 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		725696 ACTN2_HUMAN (2-387): 2.32e-122: 412: 26.00		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		211663 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		993293 ACTN3_HUMAN (23-388): 4.53e-120: 406: 27.63		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		963386 SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		963414 SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		506831 SPTB1_HUMAN (37-257): 1.25e-35: 152: 38.33		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00
+	Hs
		506841 SPTB1_HUMAN (37-257): 1.25e-35: 152: 38.33		CHM4B_HUMAN (1-232): 1.99e-44: 150: 60.78
+	Hs
		1264782 TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78		CHM4C_HUMAN (1-233): 4.84e-58: 185: 100.00