HitPredict

Interactor 1: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	18157088
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2725 Hs			1 548
+	Hs
		1052919 FLNC_HUMAN (1-2725): 0: 2507: 100.00		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		1052932 FLNC_HUMAN (1-2725): 0: 2507: 100.00		TRI54_HUMAN (1-353): 3.29e-78: 252: 62.54
+	Hs
		598307 FLNA_HUMAN (167-2725): 0: 1226: 35.27		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		261322 FLNB_HUMAN (146-2725): 0: 1198: 35.18		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		598309 FLNA_HUMAN (167-2725): 0: 1226: 35.27		TRIM6_HUMAN (13-420): 1.73e-74: 246: 13.13
+	Hs
		62677 FLNA_HUMAN (167-2725): 0: 1226: 35.27		TRI64_HUMAN (13-398): 3.94e-71: 236: 15.13
+	Hs
		598377 FLNA_HUMAN (167-2725): 0: 1226: 35.27		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Hs
		598187 FLNA_HUMAN (167-2725): 0: 1226: 35.27		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		261288 FLNB_HUMAN (146-2725): 0: 1198: 35.18		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		211440 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		TRIM3_HUMAN (7-525): 5.4e-80: 267: 16.64
+	Hs
		521464 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		211495 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		521640 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Hs
		62673 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		TRI64_HUMAN (13-398): 3.94e-71: 236: 15.13
+	Hs
		211693 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Mm
		1186640 ACTN1_MOUSE (13-382): 1.48e-122: 413: 26.30		TRI59_MOUSE (17-301): 3.82e-65: 219: 23.08
+	Hs
		521567 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		211603 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		963355 SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		1170890 SYNE1_HUMAN (33-344): 6.35e-100: 364: 28.65		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39