HitPredict

Interactor 1: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~TPR_2
Common GO terms	GO:0005739 - mitochondrion GO:0016020 - membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 618
+	Hs
		545374 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		892370 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		894004 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		1052983 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		950994 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		900465 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		436300 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120436 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		893877 FKB1A_HUMAN (101-204): 1.72e-35: 128: 32.41		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		684632 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		991528 SPAG1_HUMAN (225-336): 6.7e-16: 82.1: 20.54		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		684605 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		685039 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		915628 SPAG1_HUMAN (225-336): 6.7e-16: 82.1: 20.54		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38