Interactor 1: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Interactor 2: SMO (Q99835)
Protein smoothened (Protein Gx)
Gene: SMO

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 28298427
Identification Methods two hybrid, ubiquitin reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001933 - negative regulation of protein phosphorylation
GO:0005783 - endoplasmic reticulum
GO:0006915 - apoptotic process
GO:0007224 - smoothened signaling pathway
GO:0021904 - dorsal/ventral neural tube patterning
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 412
Hs

1 787
+ Mm

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Last updated: 15 Jul 2024