HitPredict

Interactor 1: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Interactor 2: ESYT1 (Q9BSJ8)
Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein)
Gene: ESYT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32877691, 37931956
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 1104
+	Hs
		684991 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Hs
		48352 FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32
+	Hs
		48276 STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32
+	Hs
		128842 FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18		P3C2A_HUMAN (973-1095): 9.86e-10: 65.1: 35.48
+	Hs
		128848 FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21		P3C2A_HUMAN (973-1095): 9.86e-10: 65.1: 35.48