HitPredict

Interactor 1: GAS6 (Q14393)
Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand)
Gene: GAS6

Interactor 2: CL12A (Q5QGZ9)
C-type lectin domain family 12 member A (C-type lectin-like molecule 1) (CLL-1) (Dendritic cell-associated lectin 2) (DCAL-2) (Myeloid inhibitory C-type lectin-like receptor) (MICL) (CD antigen CD371)
Gene: CLEC12A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 678 Hs			1 265
+	Hs
		1053503 GAS6_HUMAN (1-678): 3.56e-132: 406: 100.00		CL12B_HUMAN (1-259): 1.02e-68: 215: 30.29
+	Hs
		644570 GAS6_HUMAN (1-678): 3.56e-132: 406: 100.00		NKG2A_HUMAN (2-251): 3.27e-40: 140: 17.60
+	Hs
		1053534 GAS6_HUMAN (1-678): 3.56e-132: 406: 100.00		CLC2D_HUMAN (133-255): 2.28e-38: 134: 28.46
+	Hs
		644675 GAS6_HUMAN (1-678): 3.56e-132: 406: 100.00		NKG2C_HUMAN (124-251): 1.9e-27: 107: 23.44
+	Hs
		380961 SHBG_HUMAN (285-671): 1.46e-59: 207: 21.43		CLC4G_HUMAN (75-253): 1.15e-42: 148: 23.71
+	Hs
		804301 NOTC1_HUMAN (8-310): 4.42e-25: 113: 17.58		CLC2B_HUMAN (106-251): 9.68e-42: 141: 26.71
+	Hs
		942485 CNTP1_HUMAN (478-672): 7.73e-10: 64.6: 13.71		CLC4M_HUMAN (65-258): 5.02e-54: 181: 19.80
+	Hs
		530377 FBLN2_HUMAN (158-287): 8.43e-13: 73.9: 36.88		CSPG2_HUMAN (99-255): 3.28e-46: 167: 20.48
+	Hs
		957282 FBLN2_HUMAN (158-287): 8.43e-13: 73.9: 36.88		PGCB_HUMAN (100-255): 8.36e-45: 163: 16.97
+	Hs
		417469 NOTC2_HUMAN (4-276): 4.25e-13: 75.3: 12.30		FCER2_HUMAN (64-264): 5.25e-47: 161: 19.02
+	Hs
		530367 FBN1_HUMAN (118-227): 1.33e-09: 63.9: 33.33		CSPG2_HUMAN (99-255): 3.28e-46: 167: 20.48
+	Hs
		980478 NOTC2_HUMAN (4-276): 4.25e-13: 75.3: 12.30		CLC2B_HUMAN (106-251): 9.68e-42: 141: 26.71
+	Hs
		296667 SLIT2_HUMAN (78-200): 1.59e-10: 66.8: 19.84		CLC4D_HUMAN (102-256): 2.23e-41: 143: 20.48
+	Hs
		59754 LTBP1_HUMAN (58-262): 6.89e-10: 64.8: 19.27		KLRG2_HUMAN (123-250): 3.46e-30: 118: 19.53
+	Hs
		59747 CNTP1_HUMAN (478-672): 7.73e-10: 64.6: 13.71		KLRG2_HUMAN (123-250): 3.46e-30: 118: 19.53