HitPredict - High confidence protein-protein interactions

Method score	Annotation score	Interaction score
0.67	1.00	0.822

Method score

Annotation score

Interaction score

0.67

1.00

0.822

Property	Details
Experiments	36779763, 34903715, 34194039
Identification Methods	affinity chromatography technology, electron microscopy 3D single particle reconstruction
Interaction Type	physical association, direct interaction

Property

Details

Experiments

Identification Methods

affinity chromatography technology, electron microscopy 3D single particle reconstruction

Interaction Type

physical association, direct interaction

Property	Details
Interacting Pfam domains	7tm_3~7tm_3, 7tm_3~NCD3G, ANF_receptor~ANF_receptor, ANF_receptor~NCD3G, NCD3G~NCD3G
Common GO terms	GO:0001641 - group II metabotropic glutamate receptor activity GO:0004930 - G protein-coupled receptor activity GO:0005246 - calcium channel regulator activity GO:0005886 - plasma membrane GO:0007194 - negative regulation of adenylate cyclase activity and 21 others more... GO:0007216 - G protein-coupled glutamate receptor signaling pathway GO:0007268 - chemical synaptic transmission GO:0008066 - glutamate receptor activity GO:0010467 - gene expression GO:0014047 - glutamate secretion GO:0014048 - regulation of glutamate secretion GO:0014059 - regulation of dopamine secretion GO:0030424 - axon GO:0030425 - dendrite GO:0035095 - behavioral response to nicotine GO:0042220 - response to cocaine GO:0042734 - presynaptic membrane GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051966 - regulation of synaptic transmission, glutamatergic GO:0060292 - long-term synaptic depression GO:0090461 - intracellular glutamate homeostasis GO:0097110 - scaffold protein binding GO:0097449 - astrocyte projection GO:0098978 - glutamatergic synapse GO:0099171 - presynaptic modulation of chemical synaptic transmission GO:2001023 - regulation of response to drug
Homologous interactions	14