Interactor 1: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1
Interactor 2: PK3C3 (Q8NEB9)
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphatidylinositol 3-kinase p100 subunit) (Phosphoinositide-3-kinase class 3) (hVps34)
Gene: PIK3C3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.99 | 0.60 | 0.772 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18843052, 19050071, 28757208, 28846113, 28431397, 30978004, 24879154, 25275521, 35271311, 20562859, 21936852, 18628207, 16179260, 19713971, 23315026, 23878393, 25906440, 26496610, 25825496, 16390869 and 44 others
more... |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, biochemical, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000045 - autophagosome assembly GO:0000407 - phagophore assembly site GO:0005737 - cytoplasm GO:0005768 - endosome GO:0005776 - autophagosome and 15 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
