Interactor 1: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: PI3R4 (Q99570)
Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein)
Gene: PIK3R4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.764

The method score is based on:

Property Details
Experiments 24166503, 26549445, 32707033, 19050071, 23878393, 26496610, 28351972, 28059666, 19372752, 19270693, 31696776, 31955515, 35271311, 20562859, 20711182, 19270696, 18843052
Identification Methods affinity chromatography technology, biochemical, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, tandem affinity purification, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005776 - autophagosome
GO:0005829 - cytosol
GO:0006622 - protein targeting to lysosome
GO:0010506 - regulation of autophagy
GO:0016236 - macroautophagy
and 11 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 450
Hs

1 1358
+ Mm
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024