Interactor 1: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.49 0.60 0.543

The method score is based on:

Property Details
Experiments 20057503
Identification Methods two hybrid, pull down, anti tag coimmunoprecipitation, fluorescent resonance energy transfer
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000423 - mitophagy
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0031625 - ubiquitin protein ligase binding
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 450
Hs

1 581
+ Hs
+ Hs

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Last updated: 15 Jul 2024