Interactor 1: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1
Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.762 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24587252, 33562550, 23974797, 20921139, 25499913, 30258449, 23954414, 20562859, 21358617, 20711182, 25438055, 20417604 |
| Identification Methods | affinity chromatography technology, enzymatic study, pull down, fluorescent resonance energy transfer, anti bait coimmunoprecipitation, two hybrid, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000045 - autophagosome assembly GO:0000423 - mitophagy GO:0005737 - cytoplasm GO:0005776 - autophagosome GO:0005783 - endoplasmic reticulum and 8 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
