HitPredict

Interactor 1: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: NALP2 (Q9NX02)
NACHT, LRR and PYD domains-containing protein 2 (Nucleotide-binding site protein 1) (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2)
Gene: NLRP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 450 Hs			1 1062
+	Hs
		111633 K7ER46_HUMAN (152-232): 2.52e-15: 74.5: 96.30		NALP2_HUMAN (1-1062): 0: 785: 100.00
+	Hs
		1054189 BECN1_HUMAN (1-450): 0: 645: 100.00		NLRP3_HUMAN (847-1058): 2.4e-36: 151: 33.49
+	Hs
		1054157 BECN1_HUMAN (1-450): 0: 645: 100.00		NLRX1_HUMAN (839-1034): 4.6e-12: 72.4: 22.73
+	Hs
		886378 BECN1_HUMAN (1-450): 0: 645: 100.00		NLRP6_HUMAN (936-1051): 1.52e-10: 67.4: 26.27
+	Hs
		886438 BECN1_HUMAN (1-450): 0: 645: 100.00		NALP5_HUMAN (452-755): 2.3e-10: 67: 12.50
+	Hs
		111632 K7ER46_HUMAN (152-232): 2.52e-15: 74.5: 96.30		NALP5_HUMAN (452-755): 2.3e-10: 67: 12.50