HitPredict

Interactor 1: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Interactor 2: SF01 (Q15637)
Splicing factor 1 (Mammalian branch point-binding protein) (BBP) (mBBP) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Zinc finger protein 162)
Gene: SF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	28302793, 26420826
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~SF1-HH
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0048024 - regulation of mRNA splicing, via spliceosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 639
+	Hs
		1075767 PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41		SF01_HUMAN (1-639): 2.99e-88: 289: 100.00
+	Hs
		1054376 RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00		KHDR2_HUMAN (82-431): 1.92e-42: 158: 19.17
+	Mm
		1141330 RBM39_MOUSE (1-530): 5.89e-101: 316: 99.81		KHDR1_MOUSE (81-435): 1.48e-30: 126: 17.58
+	Hs
		991764 RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92
+	Hs
		1073577 SF3B4_HUMAN (238-395): 5.66e-23: 103: 22.79		SF01_HUMAN (1-639): 2.99e-88: 289: 100.00
+	Hs
		1075720 DAZP1_HUMAN (243-329): 7.18e-19: 90.6: 29.89		SF01_HUMAN (1-639): 2.99e-88: 289: 100.00
+	Sc
		376973 PABP_YEAST (40-441): 6.66e-53: 190: 12.17		BBP_YEAST (20-472): 1.32e-49: 181: 32.75
+	Hs
		162058 HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93		SF01_HUMAN (1-639): 2.99e-88: 289: 100.00
+	Hs
		1075719 MSI2H_HUMAN (149-309): 3.89e-15: 78.6: 28.57		SF01_HUMAN (1-639): 2.99e-88: 289: 100.00
+	Hs
		1073584 SF3B4_HUMAN (238-395): 5.66e-23: 103: 22.79		KHDR2_HUMAN (82-431): 1.92e-42: 158: 19.17
+	Hs
		1020313 ELAV2_HUMAN (434-530): 7.45e-16: 81.1: 10.89		QKI_HUMAN (74-357): 5.07e-42: 157: 21.97
+	Hs
		162069 HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93		KHDR2_HUMAN (82-431): 1.92e-42: 158: 19.17
+	Hs
		1139252 MSI2H_HUMAN (149-309): 3.89e-15: 78.6: 28.57		KHDR2_HUMAN (82-431): 1.92e-42: 158: 19.17
+	Hs
		1288210 MSI2H_HUMAN (149-309): 3.89e-15: 78.6: 28.57		QKI_HUMAN (74-357): 5.07e-42: 157: 21.97
+	Hs
		1198917 RBM23_HUMAN (422-503): 5.12e-10: 63.8: 15.12		QKI_HUMAN (74-357): 5.07e-42: 157: 21.97
+	Hs
		162020 HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93		KHDR1_HUMAN (135-252): 2.61e-25: 111: 29.92