HitPredict

Interactor 1: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	24457600, 36517590
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 746
+	Hs
		516536 PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		1031345 PABP4_HUMAN (41-422): 3.94e-60: 211: 17.22		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		1080225 DAZP1_HUMAN (243-329): 7.18e-19: 90.6: 29.89		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		162061 HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		1198914 RBM23_HUMAN (422-503): 5.12e-10: 63.8: 15.12		EZH1_HUMAN (15-745): 0: 745: 63.48
+	Hs
		1054567 RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00		SETD2_HUMAN (190-732): 2.07e-89: 310: 16.64
+	Hs
		516645 PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08		NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82
+	Sc
		376833 PABP_YEAST (40-441): 6.66e-53: 190: 12.17		SET2_YEAST (470-733): 1.22e-59: 216: 25.56
+	Dm
		1129084 Q9VM49_DROME (124-530): 4.01e-72: 242: 57.84		SET1_DROME (611-732): 1.27e-18: 93.2: 38.71