HitPredict

Interactor 1: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28302793
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0006397 - mRNA processing GO:0016607 - nuclear speck
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 551
+	Hs
		1031328 RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		516518 RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		162062 HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93		CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00
+	Hs
		1031490 PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		516495 PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		516730 PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		516339 PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		516689 PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08		PABP3_HUMAN (82-518): 1.28e-22: 103: 15.56
+	Hs
		474021 PAB4L_HUMAN (247-522): 4e-43: 159: 18.15		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		1073600 SF3B4_HUMAN (238-395): 5.66e-23: 103: 22.79		CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82
+	Zm
		8143 A0A1D6ELH4_MAIZE (251-530): 9.87e-38: 149: 16.96		A0A1D6ELH4_MAIZE (60-456): 7.52e-26: 113: 13.55
+	Sc
		376562 PABP_YEAST (40-441): 6.66e-53: 190: 12.17		PABP_YEAST (82-174): 3.01e-12: 71.1: 27.96
+	Hs
		1020249 ELAV2_HUMAN (434-530): 7.45e-16: 81.1: 10.89		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		162035 HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		516484 ELAV2_HUMAN (434-530): 7.45e-16: 81.1: 10.89		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		161948 HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		297862 SF3B4_HUMAN (238-395): 5.66e-23: 103: 22.79		SC24D_HUMAN (131-353): 2.02e-11: 68.8: 21.49
+	Hs
		1335172 MAN1_HUMAN (423-530): 8.66e-21: 98.6: 43.52		CDHR5_HUMAN (181-417): 5.34e-09: 61.1: 18.99