Interactor 1: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Interactor 2: SRPK1 (Q96SB4)
SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)
Gene: SRPK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.921

The method score is based on:

Property Details
Experiments 28302793, 35271311, 32707033, 23602568
Identification Methods affinity chromatography technology, enzymatic study, pull down, tandem affinity purification, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type physical association, direct interaction, association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RRM_1
Common GO terms GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0008380 - RNA splicing
GO:0016607 - nuclear speck
GO:0048024 - regulation of mRNA splicing, via spliceosome
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 530
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1 655
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Last updated: 15 Jul 2024