HitPredict

Interactor 1: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 1191
+	Hs
		1335224 PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		516698 PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1031467 PABP4_HUMAN (41-422): 3.94e-60: 211: 17.22		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1329984 PABP3_HUMAN (41-435): 1.54e-59: 209: 17.08		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		162161 HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1288220 MSI2H_HUMAN (149-309): 3.89e-15: 78.6: 28.57		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1054374 RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136342 PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		516550 PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1031360 PABP4_HUMAN (41-422): 3.94e-60: 211: 17.22		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136287 PABP3_HUMAN (41-435): 1.54e-59: 209: 17.08		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		162068 HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136221 MSI2H_HUMAN (149-309): 3.89e-15: 78.6: 28.57		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1054314 RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Sp
		143391 RSD1_SCHPO (18-521): 2.36e-85: 277: 31.38		LKH1_SCHPO (527-814): 6.12e-09: 62.2: 14.78
+	Hs
		516595 PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08		KMT2C_HUMAN (351-895): 4.49e-14: 79.7: 9.35
+	Dm
		1367870 Q9W424_DROME (148-329): 2.25e-15: 79.3: 28.80		Q9VID9_DROME (327-999): 8.7e-29: 127: 10.00
+	Hs
		325741 SF3B4_HUMAN (238-395): 5.66e-23: 103: 22.79		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Sp
		784819 GAR2_SCHPO (132-330): 2.12e-15: 80.9: 32.70		LKH1_SCHPO (527-814): 6.12e-09: 62.2: 14.78
+	Hs
		257643 RBM23_HUMAN (422-503): 5.12e-10: 63.8: 15.12		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44