Interactor 1: SKR1 (G5ECU1)
Skp1-related protein
Gene: skr-1

Interactor 2: FBSP1 (Q18223)
F-box/SPRY domain-containing protein 1 (F-box synaptic protein 1)
Gene: fsn-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 15208641, 19123269, 11864566, 18692475, unassigned701
Identification Methods affinity chromatography technology, two hybrid, two hybrid array, two hybrid pooling approach, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box~Skp1
Common GO terms GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0010629 - negative regulation of gene expression
GO:0019005 - SCF ubiquitin ligase complex
GO:0043518 - negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0090128 - regulation of synapse maturation
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 176
Ce

1 332
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024