HitPredict

Interactor 1: KCJ12 (Q14500)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: KCNJ12

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	15024025, 14960569
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 433 Hs			1 197
+	Hs
		1054726 KCJ12_HUMAN (1-433): 0: 762: 100.00		LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69
+	Hs
		158284 KCJ12_HUMAN (1-433): 0: 762: 100.00		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Rn
		852401 KCJ12_RAT (1-433): 0: 726: 95.84		LIN7C_RAT (1-197): 1.38e-57: 181: 100.00
+	Rn
		852402 KCJ12_RAT (1-433): 0: 726: 95.84		LIN7A_RAT (6-194): 4.73e-51: 166: 80.42
+	Hs
		1033871 KCJ12_HUMAN (1-433): 0: 762: 100.00		SNTB2_HUMAN (61-179): 3e-32: 123: 35.25
+	Hs
		1033833 KCJ12_HUMAN (1-433): 0: 762: 100.00		SNTA1_HUMAN (40-186): 6.39e-31: 119: 26.80
+	Hs
		1046429 KCJ12_HUMAN (1-433): 0: 762: 100.00		SNTB1_HUMAN (65-179): 5.68e-31: 119: 35.90
+	Hs
		159210 KCJ12_HUMAN (1-433): 0: 762: 100.00		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		1054723 KCJ12_HUMAN (1-433): 0: 762: 100.00		DLG2_HUMAN (23-196): 1.68e-25: 104: 23.63
+	Hs
		942342 KCJ12_HUMAN (1-433): 0: 762: 100.00		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		1021490 KCJ12_HUMAN (1-433): 0: 762: 100.00		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		80982 KCJ18_HUMAN (1-433): 0: 757: 98.61		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		1054724 KCJ12_HUMAN (1-433): 0: 762: 100.00		DLG3_HUMAN (74-164): 2.8e-20: 89.8: 35.42
+	Rn
		852400 KCJ12_RAT (1-433): 0: 726: 95.84		DLG2_RAT (23-196): 1.1e-25: 105: 23.63
+	Rn
		677769 KCJ12_RAT (1-433): 0: 726: 95.84		DLG4_RAT (59-195): 2.17e-23: 98.7: 26.76
+	Rn
		852397 KCJ12_RAT (1-433): 0: 726: 95.84		DLG1_RAT (94-178): 2.77e-21: 92.5: 37.78
+	Rn
		852399 KCJ12_RAT (1-433): 0: 726: 95.84		DLG3_RAT (60-164): 3.16e-21: 92.5: 32.73
+	Hs
		929765 KCNJ2_HUMAN (6-433): 0: 686: 70.70		SNTA1_HUMAN (40-186): 6.39e-31: 119: 26.80
+	Hs
		929762 KCNJ2_HUMAN (6-433): 0: 686: 70.70		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		929764 KCNJ2_HUMAN (6-433): 0: 686: 70.70		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60