HitPredict

Interactor 1: CASL (Q14511)
Enhancer of filamentation 1 (hEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (Cas scaffolding protein family member 2) (CASS2) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (Renal carcinoma antigen NY-REN-12) (p105) [Cleaved into: Enhancer of filamentation 1 p55]
Gene: NEDD9

Interactor 2: SMAD2 (Q15796)
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
Gene: SMAD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11118211
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 834 Hs			1 467
+	Hs
		950182 CASL_HUMAN (1-834): 0: 614: 100.00		SMAD3_HUMAN (1-467): 0: 617: 83.94
+	Hs
		1054770 CASL_HUMAN (1-834): 0: 614: 100.00		SMAD1_HUMAN (1-467): 0: 565: 55.53
+	Hs
		171379 BCAR1_HUMAN (1-832): 3e-84: 289: 33.44		SMAD9_HUMAN (1-467): 0: 564: 54.56
+	Hs
		1078590 KMT2C_HUMAN (137-685): 7.85e-10: 65.2: 8.48		SMAD2_HUMAN (1-467): 0: 675: 100.00
+	Hs
		171390 DYST_HUMAN (403-825): 1.13e-34: 146: 11.63		SMAD9_HUMAN (1-467): 0: 564: 54.56