HitPredict

Interactor 1: APRIO (F7VJQ1)
Alternative prion protein (AltPrP)
Gene: PRNP

Interactor 2: GRM5 (P41594)
Metabotropic glutamate receptor 5 (mGluR5)
Gene: GRM5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.50	0.512

Property	Details
Experiments	25148681
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 73 Hs			1 1212
+	Hs
		105944 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		GRM3_HUMAN (1-878): 0: 825: 41.07
+	Hs
		105932 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		GRM2_HUMAN (18-879): 0: 806: 41.32
+	Hs
		104972 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		GABR2_HUMAN (37-891): 2.18e-137: 443: 17.29
+	Hs
		106789 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		GABR1_HUMAN (17-918): 1.33e-135: 439: 15.13
+	Hs
		106081 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		MGLYR_HUMAN (424-1194): 6.06e-109: 372: 14.02