Interactor 1: HLTF (Q14527)
Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3)
Gene: HLTF

Interactor 2: RAD18 (Q9NS91)
E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18)
Gene: RAD18

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.934

The method score is based on:

Property Details
Experiments 18316726, 21396873, 23555860, 25023518, 18719106
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006281 - DNA repair
GO:0031625 - ubiquitin protein ligase binding
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1009
Hs

1 495
+ Hs
+ Hs
+ Hs
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024