Interactor 1: DHX8 (Q14562)
ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1)
Gene: DHX8

Interactor 2: DHX8 (Q14562)
ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1)
Gene: DHX8

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.740

The method score is based on:

Property Details
Experiments 22365833
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~HA2, DEAD~Helicase_C, HA2~Helicase_C, HA2~OB_NTP_bind, Helicase_C~Helicase_C, Helicase_C~OB_NTP_bind, OB_NTP_bind~OB_NTP_bind, S1~S1
Common GO terms GO:0000390 - spliceosomal complex disassembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
and 11 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1220
Hs

1 1220
+ Hs
+ Hs
+ Hs
+ Ce
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Ce
+ Ce

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Last updated: 15 Jul 2024