HitPredict

Interactor 1: DHX8 (Q14562)
ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1)
Gene: DHX8

Interactor 2: CHERP (Q8IWX8)
Calcium homeostasis endoplasmic reticulum protein (ERPROT 213-21) (SR-related CTD-associated factor 6)
Gene: CHERP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.815

Property	Details
Experiments	34079125, 22365833
Identification Methods	proximity labelling technology, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	G-patch~HA2, G-patch~Helicase_C, G-patch~OB_NTP_bind
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0006396 - RNA processing
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1220 Hs			1 916
+	Hs
		165476 DHX8_HUMAN (11-1220): 0: 1147: 100.00		SR140_HUMAN (7-365): 2.86e-39: 159: 15.75
+	Hs
		195481 DHX15_HUMAN (543-1210): 0: 811: 50.44		CHERP_HUMAN (1-916): 1.71e-149: 466: 100.00
+	Hs
		1219701 DHX40_HUMAN (566-1196): 0: 804: 42.92		CHERP_HUMAN (1-916): 1.71e-149: 466: 100.00
+	Hs
		1055419 DHX8_HUMAN (11-1220): 0: 1147: 100.00		SUGP1_HUMAN (6-151): 3.5e-10: 65.7: 27.63
+	Hs
		994243 DHX9_HUMAN (299-1177): 0: 674: 23.24		CHERP_HUMAN (1-916): 1.71e-149: 466: 100.00
+	Hs
		195449 DHX15_HUMAN (543-1210): 0: 811: 50.44		SF3A1_HUMAN (6-570): 1.14e-46: 181: 13.29
+	Hs
		165344 DHX15_HUMAN (543-1210): 0: 811: 50.44		SR140_HUMAN (7-365): 2.86e-39: 159: 15.75
+	Hs
		195482 DHX15_HUMAN (543-1210): 0: 811: 50.44		SUGP1_HUMAN (6-151): 3.5e-10: 65.7: 27.63
+	Hs
		165454 DHX9_HUMAN (299-1177): 0: 674: 23.24		SR140_HUMAN (7-365): 2.86e-39: 159: 15.75