HitPredict

Interactor 1: DHX8 (Q14562)
ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1)
Gene: DHX8

Interactor 2: DDX41 (Q9UJV9)
Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) (DEAD box protein abstrakt homolog)
Gene: DDX41

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 34079125, 25920683
Identification Methods proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, DEAD~HA2, HA2~Helicase_C, Helicase_C~Helicase_C, Helicase_C~OB_NTP_bind
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 5 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1220
Hs

1 622
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Dm
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024