HitPredict

Interactor 1: ITPR2 (Q14571)
Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)
Gene: ITPR2

Interactor 2: P2Y12 (Q9H244)
P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999)
Gene: P2RY12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 2701 Hs			1 342
+	Hs
		849666 ITPR2_HUMAN (1-2701): 0: 4407: 100.00		CCR6_HUMAN (16-314): 3.66e-89: 273: 22.88
+	Hs
		1030928 ITPR2_HUMAN (1-2701): 0: 4407: 100.00		GPR17_HUMAN (6-333): 1.6e-63: 207: 24.01
+	Hs
		849667 ITPR3_HUMAN (4-2687): 0: 3912: 64.48		CCR6_HUMAN (16-314): 3.66e-89: 273: 22.88