HitPredict

Interactor 1: ITPR3 (Q14573)
Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor)
Gene: ITPR3

Interactor 2: CABP2 (Q9NPB3)
Calcium-binding protein 2 (CaBP2)
Gene: CABP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_7~Ion_trans
Common GO terms	GO:0005509 - calcium ion binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2671 Hs			1 220
+	Hs
		484126 ITPR3_HUMAN (1-2671): 0: 4288: 100.00		CALM3_HUMAN (156-220): 2.48e-14: 69.2: 38.46
+	Hs
		648502 ITPR3_HUMAN (1-2671): 0: 4288: 100.00		CALL3_HUMAN (78-143): 1.25e-13: 67.6: 30.44
+	Hs
		361218 ITPR3_HUMAN (1-2671): 0: 4288: 100.00		TNNC2_HUMAN (154-220): 5.86e-09: 55.1: 43.28
+	Hs
		1056332 ITPR1_HUMAN (2-2663): 0: 3900: 60.67		CABP1_HUMAN (33-220): 3.84e-68: 215: 61.88
+	Hs
		1056323 ITPR1_HUMAN (2-2663): 0: 3900: 60.67		CABP2_HUMAN (1-220): 9.82e-61: 191: 100.00
+	Hs
		1055712 ITPR2_HUMAN (3-2663): 0: 3897: 64.52		CABP2_HUMAN (1-220): 9.82e-61: 191: 100.00
+	Hs
		648503 ITPR1_HUMAN (2-2663): 0: 3900: 60.67		CALL3_HUMAN (78-143): 1.25e-13: 67.6: 30.44
+	Hs
		484125 ITPR2_HUMAN (3-2663): 0: 3897: 64.52		CALM3_HUMAN (156-220): 2.48e-14: 69.2: 38.46
+	Hs
		361217 ITPR2_HUMAN (3-2663): 0: 3897: 64.52		TNNC2_HUMAN (154-220): 5.86e-09: 55.1: 43.28
+	Dm
		906671 RYR_DROME (1714-2182): 3.45e-32: 141: 19.40		CALM_DROME (156-220): 3.29e-14: 68.9: 38.46