HitPredict

Interactor 1: ELAV3 (Q14576)
ELAV-like protein 3 (Hu-antigen C) (HuC) (Paraneoplastic cerebellar degeneration-associated antigen) (Paraneoplastic limbic encephalitis antigen 21)
Gene: ELAVL3

Interactor 2: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0007399 - nervous system development GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 367 Hs			1 577
+	Hs
		128159 ELAV2_HUMAN (9-367): 1.21e-96: 293: 74.39		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Mm
		291668 ELAV4_MOUSE (1-367): 6.2e-98: 297: 73.19		IF2B1_MOUSE (1-577): 3.04e-147: 438: 99.31
+	Hs
		642802 ELAV4_HUMAN (1-367): 6.68e-98: 297: 72.92		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		1020343 ELAV2_HUMAN (9-367): 1.21e-96: 293: 74.39		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Xl
		251138 ELAV2_XENLA (2-367): 3.2e-97: 295: 75.07		IF23A_XENLA (1-577): 1.61e-140: 421: 73.06
+	Hs
		128165 PABP4_HUMAN (22-308): 1.23e-47: 172: 19.62		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1031481 PABP4_HUMAN (22-308): 1.23e-47: 172: 19.62		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		128191 ELAV1_HUMAN (2-207): 5.61e-37: 137: 16.28		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1077522 ELAV1_HUMAN (2-207): 5.61e-37: 137: 16.28		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Mm
		936696 ELAV1_MOUSE (2-207): 5e-37: 137: 16.28		IF2B3_MOUSE (1-577): 1.93e-145: 434: 71.50
+	Hs
		128037 RBMS1_HUMAN (37-209): 1.1e-23: 102: 35.75		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1020359 ELAV2_HUMAN (9-367): 1.21e-96: 293: 74.39		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Zm
		8143 A0A1D6ELH4_MAIZE (3-284): 5.25e-44: 162: 21.05		A0A1D6ELH4_MAIZE (3-574): 1.31e-58: 208: 12.40
+	Hs
		1031509 PABP4_HUMAN (22-308): 1.23e-47: 172: 19.62		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1031431 PABP4_HUMAN (22-308): 1.23e-47: 172: 19.62		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		1031417 PABP4_HUMAN (22-308): 1.23e-47: 172: 19.62		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		1077550 ELAV1_HUMAN (2-207): 5.61e-37: 137: 16.28		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1077455 ELAV1_HUMAN (2-207): 5.61e-37: 137: 16.28		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		1077442 ELAV1_HUMAN (2-207): 5.61e-37: 137: 16.28		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		1077440 ELAV1_HUMAN (2-207): 5.61e-37: 137: 16.28		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89