HitPredict

Interactor 1: ZN460 (Q14592)
Zinc finger protein 460 (Zinc finger protein 272) (Zinc finger protein HZF8)
Gene: ZNF460

Interactor 2: HIC2 (Q96JB3)
Hypermethylated in cancer 2 protein (Hic-2) (HIC1-related gene on chromosome 22 protein) (Hic-3) (Zinc finger and BTB domain-containing protein 30)
Gene: HIC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	zf-C2H2~zf-C2H2
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 562 Hs			1 615
+	Hs
		1305550 ZN184_HUMAN (53-558): 0: 673: 38.70		ZNF71_HUMAN (173-614): 3.39e-138: 413: 19.56
+	Hs
		1055978 ZN460_HUMAN (1-562): 0: 692: 100.00		ZN251_HUMAN (301-588): 1.45e-70: 242: 16.57
+	Hs
		67867 ZN460_HUMAN (1-562): 0: 692: 100.00		ZN724_HUMAN (465-615): 5.55e-37: 147: 27.82
+	Hs
		264766 ZN479_HUMAN (104-451): 1.51e-148: 439: 45.58		ZN254_HUMAN (147-614): 7.33e-126: 387: 16.92
+	Hs
		563267 ZN708_HUMAN (62-507): 0: 565: 42.76		ZN543_HUMAN (67-404): 4.35e-73: 247: 9.15
+	Hs
		549163 ZN460_HUMAN (1-562): 0: 692: 100.00		ZN250_HUMAN (107-385): 5.86e-27: 117: 9.57
+	Hs
		1055903 ZN460_HUMAN (1-562): 0: 692: 100.00		ZN267_HUMAN (501-612): 5.01e-15: 80.5: 30.28
+	Hs
		977954 ZN460_HUMAN (1-562): 0: 692: 100.00		ZNF92_HUMAN (256-459): 3.24e-14: 77.8: 10.24
+	Hs
		200253 ZN460_HUMAN (1-562): 0: 692: 100.00		ZN264_HUMAN (127-361): 4.84e-13: 74: 9.36
+	Hs
		1055984 ZN460_HUMAN (1-562): 0: 692: 100.00		ZN430_HUMAN (301-431): 3.01e-12: 71.3: 11.18
+	Hs
		150367 ZN460_HUMAN (1-562): 0: 692: 100.00		ZN195_HUMAN (499-594): 5.38e-09: 61.2: 32.29
+	Hs
		983758 ZNF91_HUMAN (55-527): 0: 593: 41.60		ZKSC8_HUMAN (272-424): 7.93e-19: 92.1: 13.64
+	Hs
		563270 ZN708_HUMAN (62-507): 0: 565: 42.76		ZKSC8_HUMAN (272-424): 7.93e-19: 92.1: 13.64
+	Hs
		977957 ZNF92_HUMAN (67-521): 0: 541: 40.83		ZKSC8_HUMAN (272-424): 7.93e-19: 92.1: 13.64
+	Hs
		200254 ZN805_HUMAN (304-562): 8.44e-128: 389: 43.24		ZN264_HUMAN (127-361): 4.84e-13: 74: 9.36
+	Hs
		150385 ZN383_HUMAN (230-531): 2.23e-95: 300: 50.33		ZN195_HUMAN (499-594): 5.38e-09: 61.2: 32.29
+	Hs
		64162 ZN726_HUMAN (53-275): 3.98e-70: 238: 28.76		ZN430_HUMAN (301-431): 3.01e-12: 71.3: 11.18
+	Hs
		240854 ZNF71_HUMAN (164-275): 1.02e-26: 115: 49.57		Z354A_HUMAN (501-612): 4.15e-14: 77.4: 35.71