HitPredict

Interactor 1: NBR1 (Q14596)
Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
Gene: NBR1

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.746

Property	Details
Experiments	31857374, 33545068, 29149599, 24879152, 19250911, 23022382, 20562859
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome GO:0005829 - cytosol GO:0016236 - macroautophagy GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 966 Hs			1 125
+	Hs
		1056129 NBR1_HUMAN (1-966): 0: 1811: 100.00		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891147 NBR1_HUMAN (1-966): 0: 1811: 100.00		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306175 NBR1_HUMAN (1-966): 0: 1811: 100.00		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1056120 NBR1_HUMAN (1-966): 0: 1811: 100.00		MLP3C_HUMAN (1-120): 2.08e-51: 161: 55.00
+	Hs
		1056126 NBR1_HUMAN (1-966): 0: 1811: 100.00		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Mm
		956458 NBR1_MOUSE (1-966): 0: 1731: 82.15		MLP3A_MOUSE (1-120): 8.21e-55: 168: 82.50
+	At
		1227908 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8A_ARATH (3-125): 4.4e-60: 182: 37.40
+	At
		1351949 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8D_ARATH (3-121): 4.76e-60: 182: 35.29
+	At
		1248233 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8C_ARATH (3-121): 8.25e-60: 181: 36.13
+	At
		1258022 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8F_ARATH (3-120): 1.05e-58: 178: 37.29
+	At
		1351950 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8B_ARATH (4-120): 7.21e-59: 178: 35.90
+	At
		1339372 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8I_ARATH (5-120): 5.04e-52: 161: 41.38