HitPredict

Interactor 1: PLSI (Q14651)
Plastin-1 (Intestine-specific plastin) (I-plastin)
Gene: PLS1

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 629 Hs			1 779
+	Hs
		533345 PLST_HUMAN (2-628): 0: 641: 75.32		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		533245 PLSL_HUMAN (3-628): 0: 629: 73.53		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1056366 PLSI_HUMAN (1-629): 0: 649: 100.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		533310 PLST_HUMAN (2-628): 0: 641: 75.32		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1056372 PLSI_HUMAN (1-629): 0: 649: 100.00		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		533317 PLST_HUMAN (2-628): 0: 641: 75.32		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		974145 DYST_HUMAN (369-628): 2.56e-67: 241: 21.51		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1331636 MACF1_HUMAN (381-620): 5.1e-49: 187: 21.05		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1068666 PLEC_HUMAN (374-628): 1.14e-48: 186: 20.91		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		211664 ACTN4_HUMAN (379-626): 3.78e-49: 186: 19.69		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		521613 ACTN1_HUMAN (378-626): 7.32e-49: 185: 19.61		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		211598 ACTN4_HUMAN (379-626): 3.78e-49: 186: 19.69		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		521561 ACTN1_HUMAN (378-626): 7.32e-49: 185: 19.61		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Mm
		1148443 Q68FG2_MOUSE (382-629): 4.62e-49: 187: 21.09		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Hs
		57984 ACTN3_HUMAN (391-626): 2.82e-50: 189: 20.66		A2RRN7_HUMAN (57-428): 4.21e-47: 181: 12.44
+	Hs
		993303 ACTN3_HUMAN (391-626): 2.82e-50: 189: 20.66		CAPS1_HUMAN (11-428): 3.69e-46: 180: 11.26
+	Hs
		211597 ACTN4_HUMAN (379-626): 3.78e-49: 186: 19.69		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		1068669 PLEC_HUMAN (374-628): 1.14e-48: 186: 20.91		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		211612 ACTN4_HUMAN (379-626): 3.78e-49: 186: 19.69		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		521574 ACTN1_HUMAN (378-626): 7.32e-49: 185: 19.61		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93